nucleolar DNA - definitie. Wat is nucleolar DNA
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Wat (wie) is nucleolar DNA - definitie

A REGION OF A CHROMOSOME WHERE NUCLEOLI FORM DURING INTERPHASE, AND WHERE GENES ENCODING THE LARGEST RRNA PRECURSOR TRANSCRIPT ARE TANDEMLY ARRAYED.
Nucleolar organizer; Nucleolar organizer region; Nucleolar Organizing Regions; Nucleolar Organizing Region; Nucleolar Organization Region; Nucleolar organization region; Nucleolar organizer regions; Nucleolar organizing regions; Nucleolar organizing region
  • [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973289/figure/MCSTAYGAD283838F1/ The location of NORs and the nucleolar cycle in human cells.]
  • [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847771/figure/F4/ The DJ forms a perinucleolar anchor for rDNA repeats.]
  • Silver-stained nucleolus organizer region (arrow) at the tip of a chromosome of the Gecko ''[[Lepidodactylus lugubris]]''

DNA glycosylase         
  • Hydrolysis of cytosine to uracil
ENZYMES INVOLVED IN BASE EXCISION REPAIR
GO system; Dna glycosylases; Dna glycosylase; DNA glycosylases; Dna Glycosylase
DNA glycosylases are a family of enzymes involved in base excision repair, classified under EC number EC 3.2.
https://en.wikipedia.org/wiki/DNA_glycosylase
DNA bank         
STORAGE OF PHYSICAL DNA SAMPLES
Dna bank; DNA Bank
DNA banking is the secure, long term storage of an individual’s genetic material. DNA is most commonly extracted from blood, but can also be obtained from saliva and other tissues.
https://en.wikipedia.org/wiki/DNA_bank
DNA supercoil         
  • Supercoiled structure of circular DNA molecules with low writhe. The helical nature of the DNA duplex is omitted for clarity.
  • Figure showing the various conformational changes which are observed in circular DNA at different pH. At a pH of about 12 (alkaline), there is a dip in the sedimentation coefficient, followed by a relentless increase up to a pH of about 13, at which pH the structure converts into the mysterious "Form IV".
  • Stochastic, prokaryotic model of the dynamics of RNA production and transcription locking at the promoter region, due to PSB.
  • Drawing showing the difference between a circular DNA chromosome (a plasmid) with a secondary helical twist only, and one containing an additional tertiary superhelical twist superimposed on the secondary helical winding.
  • Supercoiled structure of linear DNA molecules with constrained ends. The helical nature of the DNA duplex is omitted for clarity.
  • Illustration of how cold shock affects the supercoiling state of the DNA, by blocking the activity of Gyrase. The signs ‘ − ’ and ‘+’ represent negative and positive supercoiling, respectively. Created with BioRender.com. Also shown is a stochastic model of gene expression during cold shock as a function of the global DNA supercoiling state. The transition from ON to OFF of the promoter (P) causes the locking of transcription (i.e. RNA production). When ON, the promoter can produce RNA, from which proteins can be produced. RNA and proteins are always subject to degradation or dilution due to cell division.
COMPRESSED DNA LOOP SUPERCOILED BY PROKARYOTES TO FIT WITHIN A SMALL SPACE
Supercoil; Supercoiling; Dna, circular; Supercoiling of DNA; Positive supercoiling; Twist (DNA); Writhe (DNA); Supercoiled; Superhelical DNA energetics; Surface wrapping of DNA; DNA supercoiling; Circular genome; Supercoiled DNA; Superhelical DNA; Supertwisted DNA; Plectonemic supercoil; Linking number of DNA; Negative supercoiling; Superhelical dna
DNA supercoiling refers to the amount of twist in a particular DNA strand, which determines the amount of strain on it. A given strand may be "positively supercoiled" or "negatively supercoiled" (more or less tightly wound).
https://en.wikipedia.org/wiki/DNA_supercoil

Wikipedia

Nucleolus organizer region

Nucleolus organizer regions (NORs) are chromosomal regions crucial for the formation of the nucleolus. In humans, the NORs are located on the short arms of the acrocentric chromosomes 13, 14, 15, 21 and 22, the genes RNR1, RNR2, RNR3, RNR4, and RNR5 respectively. These regions code for 5.8S, 18S, and 28S ribosomal RNA. The NORs are "sandwiched" between the repetitive, heterochromatic DNA sequences of the centromeres and telomeres. The exact sequence of these regions is not included in the human reference genome as of 2016 or the GRCh38.p10 released January 6, 2017. On 28 February 2019, GRCh38.p13 was released, which added the NOR sequences for the short arms of chromosomes 13, 14, 15, 21, and 22. However, it is known that NORs contain tandem copies of ribosomal DNA (rDNA) genes. Some sequences of flanking sequences proximal and distal to NORs have been reported. The NORs of a loris have been reported to be highly variable. There are also DNA sequences related to rDNA that are on other chromosomes and may be involved in nucleoli formation.

https://en.wikipedia.org/wiki/Nucleolus organizer region
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